Cardiac Sarcoidosis

Cardiac sarcoidosis is a serious inflammatory disease in the heart that can cause heart failure and arrhythmias. There is limited knowledge about one type of immune cells in the heart that may be causing the disease, called T cells. This project aims to use high-throughput immune profiling technology to study the types of T-cells in the heart during cardiac sarcoidosis, and test whether blocking novel druggable pathways direct T-cells away from the heart and reduce cardiac inflammation.

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Funding: NHBLI Katz R01, Philanthropy